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faculty profile |
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Research Description:
The research conducted in my lab aims to further our understanding of the metastasis processes, specifically the interactions of the tumor mass with the host vasculature and the host immune system during the cancer progression. Additionally, this research is committed to the advancement of molecular diagnosis tools to reliably evaluate the likelihood of metastasis in cancer patients. |
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Recent Publications:
D. Dreau, A. Karaa, C. Culberson, H. Wyan, I.H. McKillop, M.G. Clemens (2006). Bosentan inhibits tumor vascularization and bone metastasis in an immune competent skin-fold chamber model of breast carcinoma cell metastasis. Clinical & Experimental Metastasis, In press.
A.M. Carbonell, B.D. Matthews, D. Dreau, M. Foster, C.E. Austin, K.W. Kercher, R.F. Sing, B.T. Heniford (2004). The susceptibility of prosthetic biomaterials to infection. Surgical Endoscopy, 19(3):430-5.
S.S. Brar, C. Grigg, K.S. Wilson, W.D. Holder Jr, D. Dreau, C. Austin, M. Foster, A.J. Ghio, A.R. Whorton, G.W. Stowell, L.B. Whittall, R.R. Whittle, D.P. White, T.P. Kennedy (2004). Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease. Molecular Cancer Therapeutics, 3(9):1049-60.
D. Dreau, M. Foster, M. Hogg, J. Swiggett, W.D. Holder, R.L. White (2000). Angiogenic and immune parameters during recombinant interferon-alpha2b adjuvant treatment in patients with melanoma. Oncology Research, 12(5):241-51.
D. Dreau, M. Foster, D.S. Morton, N. Fowler, K. Kinney, G. Sonnenfeld (2000). Immune alterations in three mouse strains following 2-deoxy-D-glucose administration. Physiology & Behavior, 70(5):513-20.
A.K. Bosserhoff, D. Dreau, R. Hein, M. Landthaler, W.D. Holder, R. Buettner (2001). Melanoma inhibitory activity (MIA), a serological marker of malignant melanoma. Recent Results in Cancer Research, 158:158-68.
D. Dreau, C. Culberson, S. Wyatt S, W.D. Holder Jr (2000). Human papilloma virus in melanoma biopsy specimens and its relation to melanoma progression. Annals of Surgery, 231(5):664-71.
D. Dreau, D.S. Morton, M. Foster, N. Fowler, G. Sonnenfeld (2000). Effects of 2-deoxy-D-glucose administration on cytokine production in BDF1 mice. Journal of Interferon & Cytokine Research, 20(2):247-55.
D. Dreau, G. Sonnenfeld, N. Fowler, D.S. Morton, M. Lyte (1999). Effects of social conflict on immune responses and E. coli growth within closed chambers in mice. Physiology & Behavior, 67(1):133-40.
D. Dreau, A.K. Bosserhoff, R.L. White, R. Buettner, W.D. Holder (1999). Melanoma-inhibitory activity protein concentrations in blood of melanoma patients treated with immunotherapy. Oncology Research, 11(1):55-61.
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Research Areas:
Bone
Brain
Cancer
Marker
Metastases
Translational
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