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faculty profile |
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| Dr. Jun-Tao Guo |
| Assistant Professor |
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Department: Computer Science | Bioinformatics Research Center |
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Office: Cameron Research Center 218 |
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Office Hours: |
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Email: jguo4@uncc.edu |
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Phone: 704-687-7492 |
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Personal Homepage |
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Research Description:
Dr. Guo’s research interests are in structural bioinformatics. More specifically, his lab focuses on developing computational methods to predict and analyze protein structure/function and their applications in solving interesting biological problems. Dr. Guo is also interested in studying the evolution of biological pathways. |
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Recent Publications:
Guo, J-T. Ellrott, K. Xu, Y. A historical perspective of template-based protein structure prediction, Protein Structure Prediction, Methods and Protocols, 3-42, 2007.
Guo, J-T. Jaromczyk, JW. Xu, Y. Analysis of Chameleon Sequences and Their Implications in Biological Processes, Proteins, 67(3):548-58, 2007.
Guo,J-T. Hall, C. Xu, Y. and Wetzel, R. Modeling Protein Aggregate Assembly and Structure, Computational Methods for Protein Structure Prediction and Modeling, 279-317, 2006.
Guo, J-T. and Xu, Y. Computational approaches to amyloid beta fibril core structures, Methods in Enzymology, 412:300-314, 2006.
Wang, P. Yan, B. Guo, J-T. Hicks, C. Xu, Y. Structural genomics analysis of alternative splicing and its application in modeling structures of alternatively spliced variants, Proc Natl Acad Sci USA, 102(52):18920-18925, 2005.
Guo, J-T. Ellrott, K. Chung, WJ. Xu, D. Passovets, S. Xu, Y. PROSPECT-PSPP: An Automatic Computational Pipeline for Protein Structure Prediction, Nucleic Acids Res., 32:W522-5, 2004.
Guo, J-T. Wetzel, R. Xu, Y. Molecular Modeling of the Core of Abeta Amyloid Fibrils, Proteins, 57(2):357-364, 2004.
Qu, Y. Guo, J-T. Olman, V. and Xu, Y. Protein Structure Prediction Using Sparse Dipolar Coupling Data, Nucleic Acids Res., 32(2):551-561, 2004.
Guo, J-T. Xu, D. Kim, D. Xu, Y. Improving the Performance of DomainParser for Structural Domain Partition Using Neural Network. Nucleic Acids Res., 31(3), 944-952, 2003.
Guo, J-T. Yu, J. Grass, D. de beer, F.C. Kindy, M.S. Inflammation Dependent Cerebral Deposition of Serum Amyloid A Protein in a Mouse Model of Amyloidosis. J. Neurosci., 22(14) 5900-5909, 2002.
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Research Areas:
Bioinformatics
Computational Biology
Evolution of Biological Pathways
Protein Structure Prediction
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