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faculty profile |
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| Dr. Nury Steuerwald |
| Research Associate Professor (adjunct) |
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Department: Biology |
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Office: Woodward Hall 485 |
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Office Hours: |
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Email: nsteuerw@uncc.edu |
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Phone: 704-687-8392 |
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Personal Homepage |
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Research Description:
My research interests include quantitative expression analysis in single oocytes with particular emphasis on cell cycle regulation and checkpoint gene expression during meiosis. I have used microarray methods to obtain a global genetic perspective of reproductive tissues in order to identify clinically useful reproductive markers. Ultimately, we wish to determine which reproductive markers are critical indicators of prognosis and the differing factors between good and poor responders of follicular stimulation during in vitro fertilization (IVF). I am also involved in the development of clinically applicable DNA microarray methods for detecting aneuploidy in single cells for use in preimplantation genetics diagnosis (PGD) and IVF. |
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Recent Publications:
N. Steuerwald, M.D. Steuerwald, J.B. Mailhes (2005). Post-ovulatory aging of mouse oocytes leads to decreased MAD2 transcripts and increased frequencies of premature centromere separation and anaphase. Mol Hum Reprod, 11(9):623-30.
N. Steuerwald (2005). Meiotic checkpoints for assessment of aneuploid gametes. Cytogenet Genome Res, 111(3-4):256-9.
N. Steuerwald, M.G. Bermudez, D. Wells, S. Munne, J. Cohen (2005). Microarray technology to assess gene expression profiles of human oocytes and embryos. 6th International Symposium on Preimplantation Genetics, London, England, May 19-22.
A. Munne, E. Velilla, P. Colls, M. Garcia Bermudez, N. Steuerwald, J. Garrisi, J. Cohen (2005). Self correction of chromosomally abnormal embryos in culture and implications for stem cell production. Fertil Steril, 84(5):1328-34.
D. Wells, M.G. Bermudez, N. Steuerwald, A. Thornhill, D.L. Walker, H. Malter, J.D.A. Delhanty, J. Cohen (2005). Association of abnormal morphology and altered gene expression in human preimplantation embryos. Fertil Steril, 84(2):343-55.
D. Wells, M.G. Bermudez, N. Steuerwald, A. Thornhill, D.L. Walker, H. Malter, J.D.A. Delhanty, J. Cohen (2005). Expression of genes regulating chromosome segregation, the cell cycle and apoptosis during human preimplantation development. Hum Reprod, 20(5):1339-48.
M.G. Bermudez, D. Wells, H. Malter, S. Munne, J. Cohen, N. Steuerwald (2004). Expression profiles of human oocytes and embryos using microarray technology. Gordon Conference: Mammalian gametogenesis and embryogenesis,Connecticut College, July 6-11.
M.G. Bermudez, D. Wells, H. Malter, S. Munne, J. Cohen, N. Steuerwald (2004). Expression profiles of individual human oocytes using microarray technology. Reprod Biomed Online, 8(3).
S. Tranguch, N. Steuerwald, Y.M. Huet-Hudson (2003). Nitric Oxide Synthase Production and Nitric Oxide Regulation of Preimplantation Embryo Development. Biol Reprod, 68:1538-44.
J.A. Barritt, M. Kokot, J. Cohen, N. Steuerwald, C.A. Brenner (2002). Quantification of human ooplasmic mitochondria. Reprod BioMed Online, 4(3):243-247.
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